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North American Porcine Reproductive and Respiratory Syndrome Viruses Inhibit Type I Interferon Production by Plasmacytoid Dendritic Cells

Although enveloped viruses typically trigger the prodigious secretion of alpha interferon (IFN-α) by plasmacytoid dendritic cells (pDC), porcine pDC remain quiescent when exposed to porcine reproductive and respiratory syndrome virus (PRRSV). This inactivity is likely due to virus-mediated interfere...

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Detalhes bibliográficos
Main Authors: Calzada-Nova, Gabriela, Schnitzlein, William M., Husmann, Robert J., Zuckermann, Federico A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067927/
https://ncbi.nlm.nih.gov/pubmed/21191013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01616-10
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