Sensing of Porcine Reproductive and Respiratory Syndrome Virus-Infected Macrophages by Plasmacytoid Dendritic Cells

Porcine reproductive and respiratory syndrome virus (PRRSV) represents a macrophage (MØ)-tropic virus which is unable to induce interferon (IFN) type I in its target cells. Nevertheless, infected pigs show a short but prominent systemic IFN alpha (IFN-α) response. A possible explanation for this dis...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: García-Nicolás, Obdulio, Auray, Gaël, Sautter, Carmen A., Rappe, Julie C. F., McCullough, Kenneth C., Ruggli, Nicolas, Summerfield, Artur
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937788/
https://ncbi.nlm.nih.gov/pubmed/27458429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.00771
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