Bivalent Junin & Machupo experimental vaccine based on alphavirus RNA replicon vector

Junin (JUNV) and Machupo (MACV), two mammalian arenaviruses placed on the 2018 WHO watch list, are prevalent in South America causing Argentine and Bolivian hemorrhagic fevers (AHF and BHF), respectively. The live attenuated JUNV vaccine, Candid #1, significantly reduced the incidence of AHF. Vaccin...

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Publicat a:Vaccine
Autors principals: Johnson, Dylan M., Jokinen, Jenny D., Wang, Min, Pfeffer, Tia, Tretyakova, Irina, Carrion, Ricardo, Griffiths, Anthony, Pushko, Peter, Lukashevich, Igor S.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112472/
https://ncbi.nlm.nih.gov/pubmed/32111526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2020.02.053
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