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Individual and Bivalent Vaccines Based on Alphavirus Replicons Protect Guinea Pigs against Infection with Lassa and Ebola Viruses

Lassa and Ebola viruses cause acute, often fatal, hemorrhagic fever diseases, for which no effective vaccines are currently available. Although lethal human disease outbreaks have been confined so far to sub-Saharan Africa, they also pose significant epidemiological concern worldwide as demonstrated...

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Detalhes bibliográficos
Main Authors: Pushko, Peter, Geisbert, Joan, Parker, Michael, Jahrling, Peter, Smith, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114754/
https://ncbi.nlm.nih.gov/pubmed/11689649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.23.11677-11685.2001
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