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Efficacy of single versus four repeated doses of praziquantel against Schistosoma mansoni infection in school-aged children from Côte d'Ivoire based on Kato-Katz and POC-CCA: An open-label, randomised controlled trial (RePST)

BACKGROUND: Preventive chemotherapy with praziquantel (PZQ) is the cornerstone of schistosomiasis control. However, a single dose of PZQ (40 mg/kg) does not cure all infections. Repeated doses of PZQ at short intervals might increase efficacy in terms of cure rate (CR) and intensity reduction rate (...

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Detaylı Bibliyografya
Yayımlandı:PLoS Negl Trop Dis
Asıl Yazarlar: Hoekstra, Pytsje T., Casacuberta-Partal, Miriam, van Lieshout, Lisette, Corstjens, Paul L. A. M., Tsonaka, Roula, Assaré, Rufin K., Silué, Kigbafori D., Meité, Aboulaye, N’Goran, Eliézer K., N’Gbesso, Yves K., Amoah, Abena S., Roestenberg, Meta, Knopp, Stefanie, Utzinger, Jürg, Coulibaly, Jean T., van Dam, Govert J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112237/
https://ncbi.nlm.nih.gov/pubmed/32196506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008189
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