Efficacy of single versus four repeated doses of praziquantel against Schistosoma mansoni infection in school-aged children from Côte d'Ivoire based on Kato-Katz and POC-CCA: An open-label, randomised controlled trial (RePST)

BACKGROUND: Preventive chemotherapy with praziquantel (PZQ) is the cornerstone of schistosomiasis control. However, a single dose of PZQ (40 mg/kg) does not cure all infections. Repeated doses of PZQ at short intervals might increase efficacy in terms of cure rate (CR) and intensity reduction rate (...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Hoekstra, Pytsje T., Casacuberta-Partal, Miriam, van Lieshout, Lisette, Corstjens, Paul L. A. M., Tsonaka, Roula, Assaré, Rufin K., Silué, Kigbafori D., Meité, Aboulaye, N’Goran, Eliézer K., N’Gbesso, Yves K., Amoah, Abena S., Roestenberg, Meta, Knopp, Stefanie, Utzinger, Jürg, Coulibaly, Jean T., van Dam, Govert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112237/
https://ncbi.nlm.nih.gov/pubmed/32196506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008189
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