TBX5 R264K acts as a modifier to develop dilated cardiomyopathy in mice independently of T-box pathway

BACKGROUND: TBX5 is a transcription factor that has an important role in development of heart. TBX5 variants in the region encoding the T-box domain have been shown to cause cardiac defects, such as atrial septal defect or ventricular septal defect, while TBX5 variants have also been identified in a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Miyao, Nariaki, Hata, Yukiko, Izumi, Hironori, Nagaoka, Ryo, Oku, Yuko, Takasaki, Ichiro, Ishikawa, Taisuke, Takarada, Shinya, Okabe, Mako, Nakaoka, Hideyuki, Ibuki, Keijiro, Ozawa, Sayaka, Yoshida, Tomoyuki, Hasegawa, Hideyuki, Makita, Naomasa, Nishida, Naoki, Mori, Hisashi, Ichida, Fukiko, Hirono, Keiichi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2020
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112173/
https://ncbi.nlm.nih.gov/pubmed/32236096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0227393
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg