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Mutagenesis of the murine hepatitis virus nsp1-coding region identifies residues important for protein processing, viral RNA synthesis, and viral replication

Despite ongoing research investigating mechanisms of coronavirus replication, functions of many viral nonstructural proteins (nsps) remain unknown. In the current study, a reverse genetic approach was used to define the role of the 28-kDa amino-terminal product (nsp1) of the gene 1 polyprotein durin...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Brockway, Sarah M., Denison, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111834/
https://ncbi.nlm.nih.gov/pubmed/16051301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2005.06.035
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