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Testing the modularity of the N-terminal amphipathic helix conserved in picornavirus 2C proteins and hepatitis C NS5A protein

The N-terminal region of the picornaviral 2C protein is predicted to fold into an amphipathic α-helix that is responsible for the protein's association with membranes in the viral RNA replication complex. We have identified a similar sequence in the N-terminal region of NS5A of hepaciviruses th...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Teterina, Natalya L., Gorbalenya, Alexander E., Egger, Denise, Bienz, Kurt, Rinaudo, Mario S., Ehrenfeld, Ellie
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111807/
https://ncbi.nlm.nih.gov/pubmed/16226781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2005.08.044
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