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Synthesis of fluorinated acyclic nucleoside phosphonates with 5-azacytosine base moiety
With respect to the strong antiviral activity of (S)-1-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine various types of its side chain fluorinated analogues were prepared. The title compound, (S)-1-[3-fluoro-2-(phosphonomethoxy)propyl]-5-azacytosine (FPMP-5-azaC) was synthesised by the condensa...
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| Udgivet i: | Tetrahedron |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier Ltd.
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7111758/ https://ncbi.nlm.nih.gov/pubmed/32287433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2019.130529 |
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