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Identification of a pH sensor in Influenza hemagglutinin using X-ray crystallography
Hemagglutnin (HA) mediates entry of influenza virus through a series of conformational changes triggered by the low pH of the endosome. The residue or combination of residues acting as pH sensors has not yet been fully elucidated. In this work, we assay pH effects on the structure of H5 HA by soakin...
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| Veröffentlicht in: | J Struct Biol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier Inc.
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7111647/ https://ncbi.nlm.nih.gov/pubmed/31689502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2019.107412 |
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