Single cell analysis reveals T cell infiltration in old neurogenic niches

The mammalian brain contains neurogenic niches comprising neural stem cells (NSCs) and other cell types. Neurogenic niches become less functional with age, but how they change during aging remains unclear. Here we perform single cell RNA-sequencing of young and old neurogenic niches in mice. Analysi...

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Publicado en:Nature
Autores principales: Dulken, Ben W., Buckley, Matthew T., Negredo, Paloma Navarro, Saligrama, Naresha, Cayrol, Romain, Leeman, Dena S., George, Benson M., Boutet, Stéphane C., Hebestreit, Katja, Pluvinage, John V., Wyss-Coray, Tony, Weissman, Irving L., Vogel, Hannes, Davis, Mark M., Brunet, Anne
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111535/
https://ncbi.nlm.nih.gov/pubmed/31270459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1362-5
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