Single cell analysis reveals T cell infiltration in old neurogenic niches

The mammalian brain contains neurogenic niches comprising neural stem cells (NSCs) and other cell types. Neurogenic niches become less functional with age, but how they change during aging remains unclear. Here we perform single cell RNA-sequencing of young and old neurogenic niches in mice. Analysi...

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Bibliografske podrobnosti
izdano v:Nature
Main Authors: Dulken, Ben W., Buckley, Matthew T., Negredo, Paloma Navarro, Saligrama, Naresha, Cayrol, Romain, Leeman, Dena S., George, Benson M., Boutet, Stéphane C., Hebestreit, Katja, Pluvinage, John V., Wyss-Coray, Tony, Weissman, Irving L., Vogel, Hannes, Davis, Mark M., Brunet, Anne
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111535/
https://ncbi.nlm.nih.gov/pubmed/31270459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1362-5
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