Single cell analysis reveals T cell infiltration in old neurogenic niches

The mammalian brain contains neurogenic niches comprising neural stem cells (NSCs) and other cell types. Neurogenic niches become less functional with age, but how they change during aging remains unclear. Here we perform single cell RNA-sequencing of young and old neurogenic niches in mice. Analysi...

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發表在:Nature
Main Authors: Dulken, Ben W., Buckley, Matthew T., Negredo, Paloma Navarro, Saligrama, Naresha, Cayrol, Romain, Leeman, Dena S., George, Benson M., Boutet, Stéphane C., Hebestreit, Katja, Pluvinage, John V., Wyss-Coray, Tony, Weissman, Irving L., Vogel, Hannes, Davis, Mark M., Brunet, Anne
格式: Artigo
語言:Inglês
出版: 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111535/
https://ncbi.nlm.nih.gov/pubmed/31270459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1362-5
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