Susceptibility to SARS coronavirus S protein-driven infection correlates with expression of angiotensin converting enzyme 2 and infection can be blocked by soluble receptor

The angiotensin converting enzyme 2 (ACE2) has been identified as a receptor for the severe acute respiratory syndrome associated coronavirus (SARS-CoV). Here we show that ACE2 expression on cell lines correlates with susceptibility to SARS-CoV S-driven infection, suggesting that ACE2 is a major rec...

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Publicado en:Biochem Biophys Res Commun
Autores principales: Hofmann, Heike, Geier, Martina, Marzi, Andrea, Krumbiegel, Mandy, Peipp, Matthias, Fey, Georg H, Gramberg, Thomas, Pöhlmann, Stefan
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier Inc. 2004
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111153/
https://ncbi.nlm.nih.gov/pubmed/15194496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2004.05.114
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