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Structure of a Herpesvirus-Encoded Cysteine Protease Reveals a Unique Class of Deubiquitinating Enzymes

All members of the herpesviridae contain within their large tegument protein a cysteine protease module that displays deubiquitinating activity. We report the crystal structure of the cysteine protease domain of murine cytomegalovirus M48 (M48(USP)) in a complex with a ubiquitin (Ub)-based suicide s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell
Prif Awduron: Schlieker, Christian, Weihofen, Wilhelm A., Frijns, Evelyne, Kattenhorn, Lisa M., Gaudet, Rachelle, Ploegh, Hidde L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier Inc. 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7110467/
https://ncbi.nlm.nih.gov/pubmed/17349955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.01.033
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