Inhibition of hepatitis C virus replication by Monascus pigment derivatives that interfere with viral RNA polymerase activity and the mevalonate biosynthesis pathway

OBJECTIVES: Hepatitis C virus (HCV) infection causes chronic liver disease and is a major public health problem worldwide. The aim of this study was to evaluate the potential of Monascus pigment derivatives, which were derived from a microbial secondary metabolite synthesized from polyketides by Mon...

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Bibliographic Details
Published in:J Antimicrob Chemother
Main Authors: Sun, Ji-Min, Kim, Seong-Jun, Kim, Geon-Woo, Rhee, Jin-Kyu, Kim, Nam Doo, Jung, Heeyong, Jeun, Jungae, Lee, Seung-Hoon, Han, Seung Hyun, Shin, Chul Soo, Oh, Jong-Won
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109977/
https://ncbi.nlm.nih.gov/pubmed/22076990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkr432
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