RUNX3 levels in human hematopoietic progenitors are regulated by aging and dictate erythroid-myeloid balance

Healthy bone marrow progenitors yield a co-ordinated balance of hematopoietic lineages. This balance shifts with aging toward enhanced granulopoiesis with diminished erythropoiesis and lymphopoiesis, changes which likely contribute to the development of bone marrow disorders in the elderly. In this...

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Publicado no:Haematologica
Main Authors: Balogh, Peter, Adelman, Emmalee R., Pluvinage, John V., Capaldo, Brian J., Freeman, Katie C., Singh, Sandeep, Elagib, Kamaleldin E., Nakamura, Yukio, Kurita, Ryo, Sashida, Goro, Zunder, Eli R., Li, Hui, Gru, Alejandro A., Price, Elizabeth A., Schrier, Stanley L., Weissman, Irving L., Figueroa, Maria E., Pang, Wendy W., Goldfarb, Adam N.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109730/
https://ncbi.nlm.nih.gov/pubmed/31171641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.208918
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