Mesenchymal stromal cells confer chemoresistance to myeloid leukemia blasts through Side Population functionality and ABC transporter activation

Targeting chemoresistant malignant cells is one of the current major challenges in oncology. Therefore, it is mandatory to refine the characteristics of these cells to monitor their survival and develop adapted therapies. This is of particular interest in acute myeloid leukemia (AML), for which the...

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Enregistré dans:
Détails bibliographiques
Publié dans:Haematologica
Auteurs principaux: Boutin, Laetitia, Arnautou, Pierre, Trignol, Aurélie, Ségot, Amandine, Farge, Thomas, Desterke, Christophe, Soave, Sabrina, Clay, Denis, Raffoux, Emmanuel, Sarry, Jean-Emmanuel, Malfuson, Jean-Valère, Lataillade, Jean-Jacques, Le Bousse-Kerdilès, Marie-Caroline, Anginot, Adrienne
Format: Artigo
Langue:Inglês
Publié: Ferrata Storti Foundation 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109715/
https://ncbi.nlm.nih.gov/pubmed/31289201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.214379
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