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Population Pharmacokinetics of Blinatumomab in Pediatric and Adult Patients with Hematological Malignancies

BACKGROUND AND OBJECTIVES: Blinatumomab (BLINCYTO(®)) is a novel bispecific T cell engager (BiTE(®)) approved in the USA for the treatment of relapsed or refractory B cell precursor acute lymphoblastic leukemia (ALL) in children and adults, as well as minimal residual disease ALL in adults. This ana...

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Bibliografiska uppgifter
I publikationen:Clin Pharmacokinet
Huvudupphovsmän: Clements, John David, Zhu, Min, Kuchimanchi, Mita, Terminello, Bianca, Doshi, Sameer
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer International Publishing 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109194/
https://ncbi.nlm.nih.gov/pubmed/31679130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-019-00823-8
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