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Exposure–response analysis of blinatumomab in patients with relapsed/refractory acute lymphoblastic leukaemia and comparison with standard of care chemotherapy

AIMS: The relationship between blinatumomab exposure and efficacy endpoints (occurrence of complete remission [CR] and duration of overall survival [OS]) or adverse events (occurrence of cytokine release syndrome [CRS] and neurological events) were investigated in adult patients with relapsed/refrac...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Kuchimanchi, Mita, Zhu, Min, Clements, John D., Doshi, Sameer
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422642/
https://ncbi.nlm.nih.gov/pubmed/30645768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13864
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