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Genetic 3′UTR variations and clinical factors significantly contribute to survival prediction and clinical response in breast cancer patients

The study describes a relationship between the 3′UTR variants, clinicopathological parameters and response to chemotherapy. We analyzed 33 germline polymorphisms in 3′UTRs of ADME genes in 305 breast cancer women treated with FAC regime. Clinical endpoints of this study were: overall survival (OS),...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Pamuła-Piłat, Jolanta, Tęcza, Karolina, Kalinowska-Herok, Magdalena, Grzybowska, Ewa
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109149/
https://ncbi.nlm.nih.gov/pubmed/32235849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-62662-z
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