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Genetic 3′UTR variations and clinical factors significantly contribute to survival prediction and clinical response in breast cancer patients

The study describes a relationship between the 3′UTR variants, clinicopathological parameters and response to chemotherapy. We analyzed 33 germline polymorphisms in 3′UTRs of ADME genes in 305 breast cancer women treated with FAC regime. Clinical endpoints of this study were: overall survival (OS),...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Pamuła-Piłat, Jolanta, Tęcza, Karolina, Kalinowska-Herok, Magdalena, Grzybowska, Ewa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109149/
https://ncbi.nlm.nih.gov/pubmed/32235849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-62662-z
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