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Genetic polymorphisms and response to 5-fluorouracil, doxorubicin and cyclophosphamide chemotherapy in breast cancer patients

Clinical resistance to chemotherapy is one of the major problems in breast cancer treatment. In this study we analyzed possible impact of 22 polymorphic variants on the treatment response in 324 breast cancer patients. Selected genes were involved in FAC chemotherapy drugs transport (ABCB1, ABCC2, A...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tecza, Karolina, Pamula-Pilat, Jolanta, Lanuszewska, Joanna, Grzybowska, Ewa
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341838/
https://ncbi.nlm.nih.gov/pubmed/27527855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11053
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