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Genetic polymorphisms and response to 5-fluorouracil, doxorubicin and cyclophosphamide chemotherapy in breast cancer patients

Clinical resistance to chemotherapy is one of the major problems in breast cancer treatment. In this study we analyzed possible impact of 22 polymorphic variants on the treatment response in 324 breast cancer patients. Selected genes were involved in FAC chemotherapy drugs transport (ABCB1, ABCC2, A...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Tecza, Karolina, Pamula-Pilat, Jolanta, Lanuszewska, Joanna, Grzybowska, Ewa
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341838/
https://ncbi.nlm.nih.gov/pubmed/27527855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11053
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