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Genetic polymorphisms and response to 5-fluorouracil, doxorubicin and cyclophosphamide chemotherapy in breast cancer patients

Clinical resistance to chemotherapy is one of the major problems in breast cancer treatment. In this study we analyzed possible impact of 22 polymorphic variants on the treatment response in 324 breast cancer patients. Selected genes were involved in FAC chemotherapy drugs transport (ABCB1, ABCC2, A...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Tecza, Karolina, Pamula-Pilat, Jolanta, Lanuszewska, Joanna, Grzybowska, Ewa
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341838/
https://ncbi.nlm.nih.gov/pubmed/27527855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11053
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