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Cancer as a disease of old age: changing mutational and microenvironmental landscapes

Why do we get cancer mostly when we are old? According to current paradigms, the answer is simple: mutations accumulate in our tissues throughout life, and some of these mutations contribute to cancers. Although mutations are necessary for cancer development, a number of studies shed light on roles...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Laconi, Ezio, Marongiu, Fabio, DeGregori, James
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109142/
https://ncbi.nlm.nih.gov/pubmed/32042067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0721-1
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