Loss of testosterone impairs anti-tumor neutrophil function

In men, the incidence of melanoma rises rapidly after age 50, and nearly two thirds of melanoma deaths are male. The immune system is known to play a key role in controlling the growth and spread of malignancies, but whether age- and sex-dependent changes in immune cell function account for this eff...

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Udgivet i:Nat Commun
Main Authors: Markman, Janet L., Porritt, Rebecca A., Wakita, Daiko, Lane, Malcolm E., Martinon, Daisy, Noval Rivas, Magali, Luu, Michael, Posadas, Edwin M., Crother, Timothy R., Arditi, Moshe
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109066/
https://ncbi.nlm.nih.gov/pubmed/32235862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15397-4
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