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Transmission characteristics of SMN from 227 spinal muscular atrophy core families in China

To define the relationship between the survival motor neuron 1 gene (SMN1) and SMN2, and explore the variability of these two genes within the generations, SMN1 and SMN2 copy numbers were determined for 227 SMA families. The association analysis indicated that there was a negative correlation betwee...

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Detalhes bibliográficos
Publicado no:J Hum Genet
Main Authors: Cao, Yanyan, Qu, Yujin, Bai, Jinli, Cheng, Miaomiao, Jin, Yuwei, Wang, Hong, Song, Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109005/
https://ncbi.nlm.nih.gov/pubmed/32051521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s10038-020-0730-1
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