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Hypoxia-induced up-regulation of miR-27a promotes paclitaxel resistance in ovarian cancer

Ovarian cancer (OC) is a malignant tumor with high mortality in women. Although cancer patients initially respond to paclitaxel chemotherapy following surgery, most patients will relapse after 12–24 months and gradually die from chemotherapy resistance. In OC, cancer cells become resistant to paclit...

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Publicat a:Biosci Rep
Autors principals: Feng, Lanlan, Shen, Fangrong, Zhou, Jinhua, Li, Yan, Jiang, Rong, Chen, Youguo
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109003/
https://ncbi.nlm.nih.gov/pubmed/32190895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20192457
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