Simultaneous tracers and a unified model of positional and mass isotopomers for quantification of metabolic flux in liver

Computational models based on the metabolism of stable isotope tracers can yield valuable insight into the metabolic basis of disease. The complexity of these models is limited by the number of tracers and the ability to characterize tracer labeling in downstream metabolites. NMR spectroscopy is ide...

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Udgivet i:Metab Eng
Main Authors: Deja, Stanislaw, Fu, Xiaorong, Fletcher, Justin A., Kucejova, Blanka, Browning, Jeffrey D., Young, Jamey D., Burgess, Shawn C.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108978/
https://ncbi.nlm.nih.gov/pubmed/31891762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2019.12.005
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