TYK2 inhibition reduces type 3 immunity and modifies disease progression in murine spondyloarthritis

Spondyloarthritis (SpA) represents a family of inflammatory diseases of the spine and peripheral joints. Ankylosing spondylitis (AS) is the prototypic form of SpA in which progressive disease can lead to fusion of the spine. Therapeutically, knowledge of type 3 immunity has translated into the devel...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Gracey, Eric, Hromadová, Dominika, Lim, Melissa, Qaiyum, Zoya, Zeng, Michael, Yao, Yuchen, Srinath, Archita, Baglaenko, Yuriy, Yeremenko, Natalia, Westlin, William, Masse, Craig, Müller, Mathias, Strobl, Birgit, Miao, Wenyan, Inman, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108927/
https://ncbi.nlm.nih.gov/pubmed/32149730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI126567
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