TYK2 inhibition reduces type 3 immunity and modifies disease progression in murine spondyloarthritis

Spondyloarthritis (SpA) represents a family of inflammatory diseases of the spine and peripheral joints. Ankylosing spondylitis (AS) is the prototypic form of SpA in which progressive disease can lead to fusion of the spine. Therapeutically, knowledge of type 3 immunity has translated into the devel...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Gracey, Eric, Hromadová, Dominika, Lim, Melissa, Qaiyum, Zoya, Zeng, Michael, Yao, Yuchen, Srinath, Archita, Baglaenko, Yuriy, Yeremenko, Natalia, Westlin, William, Masse, Craig, Müller, Mathias, Strobl, Birgit, Miao, Wenyan, Inman, Robert D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108927/
https://ncbi.nlm.nih.gov/pubmed/32149730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI126567
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