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Parathyroid hormone–dependent bone formation requires butyrate production by intestinal microbiota
Parathyroid hormone (PTH) is a critical regulator of skeletal development that promotes both bone formation and bone resorption. Using microbiota depletion by wide-spectrum antibiotics and germ-free (GF) female mice, we showed that the microbiota was required for PTH to stimulate bone formation and...
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| Veröffentlicht in: | J Clin Invest |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7108906/ https://ncbi.nlm.nih.gov/pubmed/31917685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133473 |
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