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Enasidenib drives human erythroid differentiation independently of isocitrate dehydrogenase 2

Cancer-related anemia is present in more than 60% of newly diagnosed cancer patients and is associated with substantial morbidity and high medical costs. Drugs that enhance erythropoiesis are urgently required to decrease transfusion rates and improve quality of life. Clinical studies have observed...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Dutta, Ritika, Zhang, Tian Yi, Köhnke, Thomas, Thomas, Daniel, Linde, Miles, Gars, Eric, Stafford, Melissa, Kaur, Satinder, Nakauchi, Yusuke, Yin, Raymond, Azizi, Armon, Narla, Anupama, Majeti, Ravindra
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108889/
https://ncbi.nlm.nih.gov/pubmed/31895700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133344
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