Methotrexate Polyglutamation in a Myasthenia Gravis Clinical Trial

INTRODUCTION: Methotrexate (MTX) is an immunosuppressive and anti-inflammatory drug used to treat rheumatoid arthritis (RA) and other autoimmune conditions. MTX is transported into cells, where glutamate moieties are added and is retained as methotrexate polyglutamates (MTXPGs). In the RA literature...

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Dettagli Bibliografici
Pubblicato in:Kans J Med
Autori principali: Pasnoor, Mamatha, Heim, Andrew J., Herbelin, Laura, Statland, Jeffrey, Dimachkie, Mazen M., Becker, Mara, Barohn, Richard J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: University of Kansas Medical Center 2020
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7106996/
https://ncbi.nlm.nih.gov/pubmed/32256969
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