Methotrexate Polyglutamation in a Myasthenia Gravis Clinical Trial

INTRODUCTION: Methotrexate (MTX) is an immunosuppressive and anti-inflammatory drug used to treat rheumatoid arthritis (RA) and other autoimmune conditions. MTX is transported into cells, where glutamate moieties are added and is retained as methotrexate polyglutamates (MTXPGs). In the RA literature...

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Bibliographic Details
Published in:Kans J Med
Main Authors: Pasnoor, Mamatha, Heim, Andrew J., Herbelin, Laura, Statland, Jeffrey, Dimachkie, Mazen M., Becker, Mara, Barohn, Richard J.
Format: Artigo
Language:Inglês
Published: University of Kansas Medical Center 2020
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7106996/
https://ncbi.nlm.nih.gov/pubmed/32256969
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