A randomized controlled trial of methotrexate for patients with generalized myasthenia gravis

OBJECTIVE: To determine the steroid-sparing effect of methotrexate (MTX) in patients with symptomatic generalized myasthenia gravis (MG). METHODS: We performed a 12-month multicenter, randomized, double-blind, placebo-controlled trial of MTX 20 mg orally every week vs placebo in 50 acetylcholine rec...

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Publicado en:Neurology
Main Authors: Pasnoor, Mamatha, He, Jianghua, Herbelin, Laura, Burns, Ted M., Nations, Sharon, Bril, Vera, Wang, Annabel K., Elsheikh, Bakri H., Kissel, John T., Saperstein, David, Shaibani, J. Aziz, Jackson, Carlayne, Swenson, Andrea, Howard, James F., Goyal, Namita, David, William, Wicklund, Matthew, Pulley, Michael, Becker, Mara, Mozaffar, Tahseen, Benatar, Michael, Pazcuzzi, Robert, Simpson, Ericka, Rosenfeld, Jeffrey, Dimachkie, Mazen M., Statland, Jeffrey M., Barohn, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado: Lippincott Williams & Wilkins 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932232/
https://ncbi.nlm.nih.gov/pubmed/27306628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000002795
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