OTUB1-mediated deubiquitination of FOXM1 up-regulates ECT-2 to promote tumor progression in renal cell carcinoma

BACKGROUND: OTUB1 (ovarian tumor domain protease domain-containing ubiquitin aldehyde-binding proteins)-mediated deubiquitination of FOXM1 (Forkhead box M1) participates in carcinogenesis of various tumors. We aim to investigate the effect and mechanism of OTUB1/FOXM1 on RCC (renal cell carcinoma) p...

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Bibliografiske detaljer
Udgivet i:Cell Biosci
Main Authors: Zhou, Kai, Mai, Haixing, Zheng, Song, Cai, Weizhong, Yang, Xu, Chen, Zhenlin, Zhan, Bin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7106863/
https://ncbi.nlm.nih.gov/pubmed/32257108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-020-00408-0
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