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Conformational Changes Induced by S34Y and R98C Variants in the Death Domain of Myd88
Myeloid differentiating factor 88 (Myd88) is a universal adaptor protein that plays a critical role in innate immunity by mediating TLR downstream signaling. Myd88 death domain (DD) forms an oligomeric complex by association with other DD-containing proteins such as IRAK4. Despite its universal role...
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| Publicado no: | Front Mol Biosci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7106778/ https://ncbi.nlm.nih.gov/pubmed/32266286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.00027 |
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