ADAM10 promotes cell growth, migration, and invasion in osteosarcoma via regulating E-cadherin/β-catenin signaling pathway and is regulated by miR-122-5p

BACKGROUND: Osteosarcoma is a malignant bone tumor. Increasing evidences have revealed that a disintegrin and metalloproteinase 10 (ADAM10) is implicated in tumor development. The main purpose of this study is to explore the effects of ADAM10 on osteosarcoma cell functions and the underlying molecul...

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Bibliographic Details
Published in:Cancer Cell Int
Main Authors: Yuan, Quan, Yu, Honghao, Chen, Jianhua, Song, Xiaoyu, Sun, Li
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
Subjects:
Primary Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7106760/
https://ncbi.nlm.nih.gov/pubmed/32256208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01174-2
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