LncRNA MALAT1 exhibits positive effects on nucleus pulposus cell biology in vivo and in vitro by sponging miR-503

BACKGROUND: Intervertebral disc degeneration (IDD) is characterized by the loss of nucleus pulposus cells (NPCs) and phenotypic abnormalities. Accumulating evidence suggests that long noncoding RNAs (lncRNAs) are involved in the pathogenesis of IDD. In this study, we aimed to investigate the functio...

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Veröffentlicht in:BMC Mol Cell Biol
Hauptverfasser: Zheng, Hongyu, Wang, Tingting, Li, Xiangmin, He, Wei, Gong, Zhiqiang, Lou, Zhenkai, Wang, Bing, Li, Xingguo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7106590/
https://ncbi.nlm.nih.gov/pubmed/32228440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-020-00265-2
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