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LncRNA MALAT1 exhibits positive effects on nucleus pulposus cell biology in vivo and in vitro by sponging miR-503

BACKGROUND: Intervertebral disc degeneration (IDD) is characterized by the loss of nucleus pulposus cells (NPCs) and phenotypic abnormalities. Accumulating evidence suggests that long noncoding RNAs (lncRNAs) are involved in the pathogenesis of IDD. In this study, we aimed to investigate the functio...

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Vydáno v:BMC Mol Cell Biol
Hlavní autoři: Zheng, Hongyu, Wang, Tingting, Li, Xiangmin, He, Wei, Gong, Zhiqiang, Lou, Zhenkai, Wang, Bing, Li, Xingguo
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7106590/
https://ncbi.nlm.nih.gov/pubmed/32228440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-020-00265-2
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