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Transcriptional control of regulatory T cell development and function

Regulatory T (Treg) cells differentiate from thymocytes or peripheral T cells in response to host and environmental cues, culminating in induction of the transcription factor forkhead box P3 (Foxp3) and the Treg cell-specific epigenome. An intermediate amount of antigen stimulation is required to in...

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Publié dans:Trends Immunol
Auteurs principaux: Luo, Chong T., Li, Ming O.
Format: Artigo
Langue:Inglês
Publié: Elsevier Ltd. 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7106436/
https://ncbi.nlm.nih.gov/pubmed/24016547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2013.08.003
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