Characteristics of DNMT3A mutations in acute myeloid leukemia

BACKGROUND: DNMT3A mutations occur in approximately 20% of AML cases and are associated with changes in DNA methylation. CDKN2B plays an important role in the regulation of hematopoietic progenitor cells and DNMT3A mutation is associated with CDKN2B promoter methylation. We analyzed the characterist...

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Publicat a:Blood Res
Autors principals: Park, Dong Jin, Kwon, Ahlm, Cho, Byung-Sik, Kim, Hee-Je, Hwang, Kyung-Ah, Kim, Myungshin, Kim, Yonggoo
Format: Artigo
Idioma:Inglês
Publicat: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2020
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7106122/
https://ncbi.nlm.nih.gov/pubmed/32269971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5045/br.2020.55.1.17
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