Characteristics of DNMT3A mutations in acute myeloid leukemia

BACKGROUND: DNMT3A mutations occur in approximately 20% of AML cases and are associated with changes in DNA methylation. CDKN2B plays an important role in the regulation of hematopoietic progenitor cells and DNMT3A mutation is associated with CDKN2B promoter methylation. We analyzed the characterist...

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Veröffentlicht in:Blood Res
Hauptverfasser: Park, Dong Jin, Kwon, Ahlm, Cho, Byung-Sik, Kim, Hee-Je, Hwang, Kyung-Ah, Kim, Myungshin, Kim, Yonggoo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7106122/
https://ncbi.nlm.nih.gov/pubmed/32269971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5045/br.2020.55.1.17
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