Evaluation of the safety, immunogenicity and pharmacokinetics of equine anti-SARS–CoV F(ab′)(2) in macaque()

To warrant potential clinical testing, the equine anti-SARS–CoV F(ab′)(2) requires evaluation in as many animal models as possible and a safety test in a primate model. In this study, we evaluated the pharmacokinetics, tolerance and immunity of this kind of antibody in macaques and rats. Results sho...

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Bibliografiset tiedot
Julkaisussa:Int Immunopharmacol
Päätekijät: Xu, Yunsheng, Jia, Zhengcai, Zhou, Liyun, Wang, Li, Li, Jintao, Liang, Yunfei, Zhao, TingTing, Ni, Bing, Wu, Yuzhang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier B.V. 2007
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7106090/
https://ncbi.nlm.nih.gov/pubmed/17996696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2007.09.011
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