Rapid Induction and Maintenance of Virus-Specific CD8(+) T(EMRA) and CD4(+) T(EM) Cells Following Protective Vaccination Against Dengue Virus Challenge in Humans

Dengue virus (DENV) is a mosquito-borne flavivirus that causes serious human disease. The current lack of an effective vaccine to simultaneously protect against the four serotypes of DENV in seronegative individuals is a major unmet medical need. Further, the immunological basis for protective immun...

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Udgivet i:Front Immunol
Main Authors: Graham, Nancy, Eisenhauer, Phil, Diehl, Sean A., Pierce, Kristen K., Whitehead, Stephen S., Durbin, Anna P., Kirkpatrick, Beth D., Sette, Alessandro, Weiskopf, Daniela, Boyson, Jonathan E., Botten, Jason W.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105617/
https://ncbi.nlm.nih.gov/pubmed/32265929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00479
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