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Co-evolution within structured bacterial communities results in multiple expansion of CRISPR loci and enhanced immunity

Type II CRISPR-Cas systems provide immunity against phages and plasmids that infect bacteria through the insertion of a short sequence from the invader’s genome, known as the ‘spacer’, into the CRISPR locus. Spacers are transcribed into guide RNAs that direct the Cas9 nuclease to its target on the i...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Pyenson, Nora C, Marraffini, Luciano A
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105378/
https://ncbi.nlm.nih.gov/pubmed/32223887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53078
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