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Broad targeting specificity during bacterial type III CRISPR-Cas immunity constrains viral escape
CRISPR loci are a cluster of repeats separated by short “spacer” sequences derived from prokaryotic viruses and plasmids that determine the targets of the host’s CRISPR-Cas immune response against its invaders. For type I and II CRISPR-Cas systems, single-nucleotide mutations in the seed or protospa...
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| Publicado no: | Cell Host Microbe |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5599366/ https://ncbi.nlm.nih.gov/pubmed/28826839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.07.016 |
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