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A conserved PDZ Binding Motif in aPKC interacts with Par-3 and mediates cortical polarity

Par-3 regulates animal cell polarity by targeting the Par complex proteins Par-6 and atypical Protein Kinase C (aPKC) to specific cortical sites. Although numerous physical interactions between Par-3 and the Par complex have been identified [1–6], we discovered a novel interaction between Par-3’s se...

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Publicado no:Curr Biol
Main Authors: Holly, Ryan W., Jones, Kimberly, Prehoda, Kenneth E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7104911/
https://ncbi.nlm.nih.gov/pubmed/32084408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2019.12.055
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