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Stem cell differentiation trajectories in Hydra resolved at single-cell resolution

The adult Hydra polyp continually renews all of its cells using three separate stem cell populations, but the genetic pathways enabling this homeostatic tissue maintenance are not well understood. We sequenced 24,985 Hydra single-cell transcriptomes and identified the molecular signatures of a broad...

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Bibliografiske detaljer
Udgivet i:Science
Main Authors: Siebert, Stefan, Farrell, Jeffrey A., Cazet, Jack F., Abeykoon, Yashodara, Primack, Abby S., Schnitzler, Christine E., Juliano, Celina E.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7104783/
https://ncbi.nlm.nih.gov/pubmed/31346039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aav9314
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