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Stem cell differentiation trajectories in Hydra resolved at single-cell resolution

The adult Hydra polyp continually renews all of its cells using three separate stem cell populations, but the genetic pathways enabling this homeostatic tissue maintenance are not well understood. We sequenced 24,985 Hydra single-cell transcriptomes and identified the molecular signatures of a broad...

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Détails bibliographiques
Publié dans:Science
Auteurs principaux: Siebert, Stefan, Farrell, Jeffrey A., Cazet, Jack F., Abeykoon, Yashodara, Primack, Abby S., Schnitzler, Christine E., Juliano, Celina E.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7104783/
https://ncbi.nlm.nih.gov/pubmed/31346039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aav9314
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