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The signaling pathways implicated in impairment of hepatic autophagy in glycogen storage disease type Ia
Glucose-6-phosphatase-α (G6Pase-α or G6PC) deficiency in glycogen storage disease type-Ia (GSD-Ia) leads to impaired hepatic autophagy, a recycling process important for cellular metabolism and homeostasis. Autophagy can be regulated by several energy sensing pathways, including sirtuin 1 (SIRT1), f...
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| 出版年: | Hum Mol Genet |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7104680/ https://ncbi.nlm.nih.gov/pubmed/31961433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa007 |
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