Adaptive Evolution of MERS-CoV to Species Variation in DPP4

Middle East Respiratory Syndrome Coronavirus (MERS-CoV) likely originated in bats and passed to humans through dromedary camels; however, the genetic mechanisms underlying cross-species adaptation remain poorly understood. Variation in the host receptor, dipeptidyl peptidase 4 (DPP4), can block the...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Letko, Michael, Miazgowicz, Kerri, McMinn, Rebekah, Seifert, Stephanie N., Sola, Isabel, Enjuanes, Luis, Carmody, Aaron, van Doremalen, Neeltje, Munster, Vincent
Format: Artigo
Language:Inglês
Published: Cell Press 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7104223/
https://ncbi.nlm.nih.gov/pubmed/30110630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.07.045
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